A choline salt form of theophylline
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Oxtriphylline

Item No. 24006

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-hydroxy-N,N,N-trimethyl-ethanaminium salt with 3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione
CAS Number
4499-40-5
Synonyms
  • Choline Theophylline
  • Cholinophylline
  • Zy 15061
Molecular Formula
C7H7N4O2 • C5H14NO
Formula Weight
283.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
λmax
272 nm
SMILES
CN(C(N1C)=O)C2=C(N=C[N-]2)C1=O.C[N+](CCO)(C)C
InChi Code
InChI=1S/C7H8N4O2.C5H14NO/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;1-6(2,3)4-5-7/h3H,1-2H3,(H,8,9,12);7H,4-5H2,1-3H3/q;+1/p-1
InChi Key
RLANKEDHRWMNRO-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $63

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    100 mg

    $119

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    500 mg

    $556

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    Product Description

    Oxtriphylline is a choline salt form of theophylline (Item No. 23760). It dose-dependently decreases histamine-induced contractions of isolated guinea pig trachea and increases cAMP levels in guinea pig tracheal smooth muscle cells in vitro.1 Formulations containing oxtriphylline were previously used in the treatment of asthma.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bilcíková, L., Bauer, V., and Kolena, J. The effects of methylxanthines, ethymizol, ephedrine and papaverine on guinea pig and dog trachea. Gen. Physiol. Biophys. 6(2), 137-148 (1987).