An herbicide
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Acetochlor

Item No. 24131

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-chloro-N-(ethoxymethyl)-N-(2-ethyl-6-methylphenyl)-acetamide
CAS Number
34256-82-1
Molecular Formula
C14H20ClNO2
Formula Weight
269.8
Purity
≥95%
Formulation
An oil
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly SolubleDMSO: Slightly SolubleDMSO: Soluble: ≥ 10 mg/mlEthanol: Soluble: ≥ 10 mg/mlWater: Slightly Soluble
SMILES
CC1=CC=CC(CC)=C1N(COCC)C(CCl)=O
InChi Code
InChI=1S/C14H20ClNO2/c1-4-12-8-6-7-11(3)14(12)16(10-18-5-2)13(17)9-15/h6-8H,4-5,9-10H2,1-3H3
InChi Key
VTNQPKFIQCLBDU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

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    Cayman Chemical
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    Product Description

    Acetochlor is an herbicide that completely inhibits shoot growth of oat (A. sativa) and mustard (S. alba) plants when used at a concentration of 2 kg/hectare.1 It accelerates thyroid hormone-induced metamorphosis of and alters thyroid hormone-responsive gene expression in X. laevis.2 In vivo, acetochlor induces formation of thyroid, bone, stomach, and nasal tumors in rats as well as liver and lung tumors in mice.3 Acetochlor also induces pericardial edema, thrombosis, circulation defects, and a reduction in the number of cardiomyocytes in zebrafish larvae when administered in tank water at the maximum non-lethal concentration (MNLC) of 9.6 µg/ml.4 Formulations containing acetochlor have been used as herbicides in agricultural settings.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Jablonkai, I. Alkylating reactivity and herbicidal activity of chloroacetamides. Pest. Manag. Sci. 59(4), 443-450 (2003).

    2. Crump, D., Werry, K., Veldhoen, N., et al. Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis. Environ. Health Perspect. 110(12), 1199-1205 (2002).

    3. Hurley, P.M. Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents. Environ. Health Perspect. 106(8), 437-445 (1998).

    4. Liu, H., Chu, T., Chen, L., et al. In vivo cardiovascular toxicity induced by acetochlor in zebrafish larvae. Chemosphere 181, 600-608 (2017).