A broad-spectrum carbamate insecticide
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Bendiocarb

Item No. 24133

Technical Information
Formal Name
4-(N-methylcarbamate)2,2-dimethyl-1,3-benzodioxol-4-ol
CAS Number
22781-23-3
Synonyms
  • NC 6897
  • Niomil
Molecular Formula
C11H13NO4
Formula Weight
Purity
≥98%
Formulation
A solid
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:9): 0.1 mg/mlEthanol: 5 mg/ml
SMILES
CC1(C)OC2=C(OC(NC)=O)C=CC=C2O1
InChi Code
InChI=1S/C11H13NO4/c1-11(2)15-8-6-4-5-7(9(8)16-11)14-10(13)12-3/h4-6H,1-3H3,(H,12,13)
InChi Key
XEGGRYVFLWGFHI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Bendiocarb is a broad-spectrum carbamate insecticide and an inhibitor of acetylcholinesterase (Ki = 111 nM for the human enzyme).1 It is active against several species, including second stage nymph German cockroaches (B. germanica; IC50 = <0.5 mg/ft2) and adult yellow fever mosquitoes (A. aegypti; IC50 = <0.03 mg/ft2).2 It is toxic to mammalian species with an oral LD50 value of 45 mg/kg for male rats and female mice, but it is metabolized and excreted rapidly and has a dermal LD50 of 800 mg/kg after a 24-hour exposure.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Verma, A., Wong, D.M., Islam, R., et al3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiae. Bioorg. Med. Chem. 23(6), 1321-1340 (2015).

    2. Brooker, P.J., Gates, P.S., Gillon, J., et alInsecticidal activity of certain benzodioxolyl carbamates. Pestic. Sci. 3(6), 735-744 (1972).