An organophosphate insecticide
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Chlorpyrifos-methyl

Item No. 24227

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
phosphorothioic acid O,O-dimethyl O-(3,5,6-trichloro-2-pyridinyl) ester
CAS Number
5598-13-0
Synonyms
  • OMS-1155
Molecular Formula
C7H7Cl3NO3PS
Formula Weight
322.5
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly Soluble
SMILES
ClC1=NC(OP(OC)(OC)=S)=C(Cl)C=C1Cl
InChi Code
InChI=1S/C7H7Cl3NO3PS/c1-12-15(16,13-2)14-7-5(9)3-4(8)6(10)11-7/h3H,1-2H3
InChi Key
HRBKVYFZANMGRE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

    $109

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    25 mg

    $205

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    50 mg

    $382

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    Cayman Chemical
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    Product Description

    Chlorpyrifos-methyl is an organophosphate insecticide that induces 100, 100, 63, and 97.3% mortality of the adult stored-grain pests L. bostrychophila, L. decolor, L. entomophila, and L. paeta, respectively, when applied to grain at a dose of 10 mg/kg.1 It also reduces the number of live progeny produced by L. bostrychophila, L. decolor, L. entomophila, and L. paeta by 100, 100, 30.4, and 41.1%, respectively, when applied to grain at a dose of 2.5 mg/kg. Chlorpyrifos-methyl (3 μM) reduces outgrowth of axon-like processes in mouse N2a neuroblastoma cells.2 Administration of chlorpyrifos-methyl (4-100 mg/kg) to pregnant female mice decreases H19 gene methylation in sperm as well as decreases anogenital distance and increases thymus and epididymis weights and serum testosterone levels in male offspring.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nayak, M.K., and Daglish, G.J. Combined treatments of spinosad and chlorpyrifos-methyl for management of resistant psocid pests (Psocoptera: Liposcelididae) of stored grain. Pest Manag. Sci. 63(1), 104-109 (2007).

    2. Sachana, M., Flaskos, J., and Hargreaves, A.J. Effects of chlorpyrifos and chlorpyrifos-methyl on the outgrowth of axon-like processes, tubulin, and GAP-43 in N2a Cells. Toxicol. Mech. Methods 15(6), 405-410 (2005).

    3. Shin, H.S., Seo, J.H., Jeong, S.H., et al. Effect on the H19 gene methylation of sperm and organs of offspring after chlorpyrifos-methyl exposure during organogenesis period. Environ. Toxicol. 30(12), 1355-1363 (2015).