An acaricide
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Clofentezine

Item No. 24228

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine
CAS Number
74115-24-5
Molecular Formula
C14H8Cl2N4
Formula Weight
303.1
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly Soluble
SMILES
ClC1=C(C2=NN=C(C3=CC=CC=C3Cl)N=N2)C=CC=C1
InChi Code
InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H
InChi Key
UXADOQPNKNTIHB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $49

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    50 mg

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    100 mg

    $143

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    Cayman Chemical
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    Product Description

    Clofentezine is an acaricide that has broad-spectrum activity against various plant-feeding mite species, including those of the genera Panonychus and Tetranchus.1 It lethal to wild-type, but not chitin synthase 1 (chs1) mutant, T. urticae mite eggs (LC50s = 1.2 and >5,000 mg/L, respectively). In vivo, clofentezine (13-1,000 mg/kg per day) induces formation of thyroid tumors in male rats.2 Formulations containing clofentezine have been used to control mite populations in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Demaeght, P., Osborne, E.J., Odman-Maresh, J., et al. High resolution genetic mapping uncovers chitin synthase-1 as the target-site of the structurally diverse mite growth inhibitors clofentezine, hexythiazox and etoxazole in Tetranychus urticae. Insect Biochem. Mol. Biol. 51, 52-61 (2014).

    2. Hurley, P.M. Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents. Environ. Health Perspect. 106(8), 437-445 (1998).