An organophosphate pesticide
Related Products
Labeled Version(s)
39563Coumaphos-d10
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Coumaphos

Item No. 24230

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl), phosphorothioic acid, O,O-diethyl ester
CAS Number
56-72-4
Synonyms
  • NSC 8944
Molecular Formula
C14H16ClO5PS
Formula Weight
362.8
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly solubleMethanol: Slightly soluble
SMILES
O=C1C(Cl)=C(C)C2=CC=C(OP(OCC)(OCC)=S)C=C2O1
InChi Code
InChI=1S/C14H16ClO5PS/c1-4-17-21(22,18-5-2)20-10-6-7-11-9(3)13(15)14(16)19-12(11)8-10/h6-8H,4-5H2,1-3H3
InChi Key
BXNANOICGRISHX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    50 mg

    $49

    Add

    100 mg

    $86

    Add
    Cayman Chemical
    Visit Our Environmental Toxicology Resource Center

    Explore additional resources to study natural toxins, pollutants including PFAS and 6-PPD-Q, and their biological effects.

    ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICES
    Product Description

    Coumaphos is an organophosphate pesticide.1 It is converted into the corresponding oxon metabolite in vivo, similar to other organophosphate pesticides, that inhibits acetylcholinesterase (AChE). It is active against adult, but not arrested stage, O. ostertagi helminths.2 Coumaphos is toxic to A. stephensi and A. aegypti mosquitoes when applied topically, with median lethal doses of 0.002 and 0.012 µg per female mosquito, respectively, but not when used as a contact insecticide.3 It is lethal to rats (LD50s = 41 and 16 mg/kg for male and female rats, respectively).4 Formulations containing coumaphos have been used to control pests in livestock.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Guo, J.-X., Wu, J.J.-Q., Wight, J.B., et al. Mechanistic insight into acetylcholinesterase inhibition and acute toxicity of organophosphorus compounds: A molecular modeling study. Chem. Res. Toxicol. 19(2), 209-216 (2006).

    2. Prichard, R.K. Anthelmintics and control. Vet. Parasitol. 27(1-2), 97-109 (1988).

    3. Hadaway, A.B., and Barlow, F. The toxicity of some organophosphorus compounds to adult Anopheles stephensi. Bull. World Health Organ. 28(1), 55-61 (1963).

    4. Gaines, T.B. Acute toxicity of pesticides. Toxicol. Appl. Pharmacol. 14(3), 515-534 (1969).