A metabolite and degradation product of the pesticide DDT
Related Products
Isomer(s)
24241p,p'-DDE
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

o,p'-DDE

Item No. 24235

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethenyl]-benzene
CAS Number
3424-82-6
Synonyms
  • 2,4’-DDE
  • o,p'-Dichlorodiphenyldichloroethylene
  • NSC 59908
Molecular Formula
C14H8Cl4
Formula Weight
318.0
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: HeatedMethanol: Slightly soluble
SMILES
ClC1=CC=C(/C(C2=CC=CC=C2Cl)=C(Cl)\Cl)C=C1
InChi Code
InChI=1S/C14H8Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8H
InChi Key
ZDYJWDIWLRZXDB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $36

    Add

    10 mg

    $68

    Add

    25 mg

    $159

    Add

    50 mg

    $282

    Add
    Cayman Chemical
    Visit Our Environmental Toxicology Resource Center

    Explore additional resources to study natural toxins, pollutants including PFAS and 6-PPD-Q, and their biological effects.

    ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICES
    Product Description

    o,p'-DDE is a metabolite and degradation product of the organochlorine pesticide DDT.1 It accumulates in smallmouth buffalo, channel catfish, and largemouth bass as well as sediment in the Huntsville Spring Branch-Indian Creek tributary system surrounding a DDT manufacturing plant where it is considered a persistent organic pollutant (POP). o,p'-DDE inhibits estrogen binding to rainbow trout estrogen receptors (rtERs) with an IC50 value of 3.2 μM.2 It induces concentration-dependent secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles.3 In ovo exposure to o,p'-DDE increases degeneration of ovarian follicles and reduces testicular size in Japanese medaka (O. latipes).4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Garrison, A.W., Cyterski, M., Roberts, K.D., et al. Occurrences and fate of DDT principal isomers/metabolites, DDA, and o,p'-DDD enantiomers in fish, sediment and water at a DDT-impacted superfund site. Environ. Pollut. 194, 224-234 (2014).

    2. Matthews, J., Celius, T., Halgren, R., et al. Differential estrogen receptor binding of estrogenic substances: A species comparison. J. Steroid. Biochem. Mol. Biol. 74(4), 223-234 (2000).

    3. Wójtowicz, A.K., Gregoraszczuk, E.L., Ptak, A., et al. Effect of single and repeated in vitro exposure of ovarian follicles to o,p'-DDT and p,p'-DDT and their metabolites. Pol. J. Pharmacol. 56(4), 465-472 (2004).

    4. Papoulias, D.M., Villalobos, S.A., Meadows, J.N., D.B., et al. In ovo exposure to o,p -DDE affects sexual development but not sexual differentiation in Japanese medaka (Oryzias latipes). Environ. Health Perspect. 111(1), 29-32 (2003).