An organochlorine insecticide
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Active Metabolite(s)
24255Endosulfan sulfate
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Endosulfan II

Item No. 24254

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3α,5aα,6β,9β,9aα)-6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide
CAS Number
33213-65-9
Synonyms
  • β-Endosulfan
  • Endosulfan B
Molecular Formula
C9H6Cl6O3S
Formula Weight
406.9
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly solubleMethanol: Slightly soluble
SMILES
Cl[C@]1(C2(Cl)Cl)[C@]([H])(CO[S@](OC3)=O)[C@@]3([H])[C@]2(Cl)C(Cl)=C1Cl
InChi Code
InChI=1S/C9H6Cl6O3S/c10-5-6(11)8(13)4-2-18-19(16)17-1-3(4)7(5,12)9(8,14)15/h3-4H,1-2H2/t3-,4+,7-,8+,19-
InChi Key
RDYMFSUJUZBWLH-LLXUDWAZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

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    Product Description

    Endosulfan II is an organochlorine insecticide and a stereoisomer of endosulfan I.1 It is active against a variety of insects including bollworms and tobacco budworms (LD50s = 4.14 and 4.95 mg/g, respectively).2,3 Endosulfan II binds to GABA receptors in rat brain membranes with an IC50 value of 60 nM and is less toxic to rats than endosulfan I (LD50s = 240 and 18 mg/kg, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Abalis, I.M., Eldefrawi, M.E., and Eldefrawi, A.T. High-affinity stereospecific binding of cyclodiene insecticides and γ-hexachlorocyclohexane to γ-aminobutyric acid receptors of rat brain. Pest. Biochem. Phys. 24(1), 95-102 (1985).

    2. Wolfenbarger, D.A., and Guerra, A.A. Toxicity of endosulfan and its isomers to the bollworm and tobacco budworm. J. Econ. Entomol 65(4), 1122-1123 (1972).

    3. Busvine, J.R. The insecticidal potency of γ-BHC and the chlorinated cyclodiene compounds and the significance of resistance to them. Bull. Entom. Res. 55(2), 271-288 (1964).