A bioactive sphingolipid
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Labeled Version(s)
39389C16 dihydro Ceramide-d9 (d18:0/16:0-d9)
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C16 dihydro Ceramide (d18:0/16:0)

Item No. 24369

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-hexadecanamide
CAS Number
5966-29-0
Synonyms
  • Cer(d18:0/16:0)
  • Ceramide (d18:0/16:0)
  • N-hexadecanoyl-D-erythro-Dihydrosphingosine
  • N-Palmitoyl Sphinganine
Molecular Formula
C34H69NO3
Formula Weight
539.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform:Methanol (5:1): SolubleDMSO: SolubleEthanol: Soluble
SMILES
O=C(CCCCCCCCCCCCCCC)N[C@@H](CO)[C@H](O)CCCCCCCCCCCCCCC
InChi Code
InChI=1S/C34H69NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h32-33,36-37H,3-31H2,1-2H3,(H,35,38)/t32-,33+/m0/s1
InChi Key
GCGTXOVNNFGTPQ-JHOUSYSJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    1 mg

    $39

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    5 mg

    $106

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    10 mg

    $193

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    Product Description

    C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) (Item No. 10681) that lacks the 4,5-trans double bond.1 C16 dihydro Ceramide (46 nM) inhibits C16 ceramide-induced membrane permeabilization, measured as cytochrome c oxidation, in rat liver mitochondria in a concentration-dependent manner. It also inhibits C16 ceramide-induced channel formation in liposomes. C16 dihydro ceramide is biologically inactive as a single agent, lacking the ability to induce apoptosis, cytochrome c release, or channel formation in phospholipid membranes in the absence of C16 ceramide. [Matreya, LLC. Catalog No. 2078]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Stiban, J., Fistere, D., and Colombini, M. Dihydroceramide hinders ceramide channel formation: Implications on apoptosis. Apoptosis 11(5), 773-780 (2006).