Pricing updated 2019-07-23. Prices are subject to change without notice.
C20 Sphingomyelin is a naturally occurring sphingolipid.1,2,3,4 Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin (Item No. 13104) and in human plasma where it is positively correlated with insulin resistance in obese humans.2 C20 sphingomyelin is also upregulated in the liver of a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder.1 The plasma concentration of C20 sphingomyelin is decreased in men with prostate cancer.3
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Praggastis, M., Tortelli, B., Zhang, J., et al. A murine Niemann-
2. Hanamatsu, H., Ohnishi, S., Sakai, S., et al. Altered levels of serum sphingomyelin and ceramide containing distinct acyl chains in young obese adults Nutr. Diabetes 4, e141 (2014).
Awwad, H.M., Ohlmann, C.H., Stoeckle, M., et al. Choline-
Fiedorowicz, A., Prokopiuk, S., Zendzian-