A photoreactive clickable derivative of cholesterol
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Photoclick Cholesterol

Item No. 24528

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3′β,5′α)-3′-hydroxy-spiro[3H-diazirine-3,6′-cholan]-24′-oic acid, 5-hexyn-1-yl ester
CAS Number
1485490-47-8
Synonyms
  • Click Tag™ Cholesterol
Molecular Formula
C30H46N2O3
Formula Weight
482.7
Purity
≥95%
Formulation (Request formulation change)
A 1 mg/ml solution in chloroform
Solubility(Learn about Variance in Solubility)
Chloroform: 1 mg/ml
SMILES
O[C@H]1CC[C@@]2(C)[C@](C3(N=N3)C[C@]4([H])[C@]2([H])CC[C@@]5(C)[C@@]4([H])CC[C@]5([H])[C@@H](CCC(OCCCCC#C)=O)C)([H])C1
InChi Code
InChI=1S/C30H46N2O3/c1-5-6-7-8-17-35-27(34)12-9-20(2)23-10-11-24-22-19-30(31-32-30)26-18-21(33)13-15-29(26,4)25(22)14-16-28(23,24)3/h1,20-26,33H,6-19H2,2-4H3/t20-,21+,22+,23-,24+,25+,26+,28-,29-/m1/s1
InChi Key
ZJMZIZZWLLQHJO-CHORRROKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 µg

    $224

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    250 µg

    $503

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    Product Description

    Photoclick cholesterol is a derivative of the sterol lipid cholesterol (Item No. 9003100) that contains a terminal clickable alkyne moiety and a photoactivatable diazirine group.1 It has been used in quantitative proteomic screens for sterol-binding proteins (SBPs) in S. cerevisiae.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chauhan, N., Sere, Y.Y., Sokol, A.M., et al. A PhotoClick cholesterol-based quantitative proteomics screen for cytoplasmic sterol-binding proteins in Saccharomyces cerevisiae. Yeast 37(1), 15-25 (2020).