A mitochondrial dye
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MitoLite™ Orange FX570

Item No. 25165

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Emission
575 nm
Excitation
545 nm
Formulation (Request formulation change)
A solution in DMSO
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    500 tests

    $148

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    Product Description

    MitoLite™ reagents are fluorogenic probes that can be used to label mitochondria within live cells. They are hydrophobic and easily cross live cell membranes to accumulate in mitochondria likely via the mitochondrial membrane potential gradient. MitoLite™ reagents contain a cell-retaining group, which allows them to remain in the mitochondria long-term, and their fluorescence can be measured using fluorescence microscopy, microplate fluorometry, or flow cytometry. MitoLite™ Orange FX570 has been used to label mitochondria in Hep2 cells treated with cisplatin (Item No. 13119) and N-acetyl-L-carnosine (NAC; Item No. 18817).1 MitoLite™ Orange FX570 displays excitation/emission maxima of 545/575 nm, respectively, and can be used for live and fixed cell applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lv, X., Song, D.M., Niu, Y.H., et al. Inhibition of heme oxygenase-1 enhances the chemosensitivity of laryngeal squamous cell cancer Hep-2 cells to cisplatin. Apoptosis 21(4), 489-501 (2016).