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1,2-Dilinoleoyl-sn-glycerol

Item No. 25422

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9Z,12Z-octadecadienoic acid, 1,1'-[(1S)-1-(hydroxymethyl)-1,2-ethanediyl] ester
CAS Number
24529-89-3
Synonyms
  • 1,2-Dioleoyl-sn-glycerol
Molecular Formula
C39H68O5
Formula Weight
617.0
Purity
≥95%
Formulation (Request formulation change)
A 10 mg/ml solution in acetonitrile
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 5 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 0.25 mg/ml
λmax
271 nm
SMILES
OC[C@H](OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCC/C=C\C/C=C\CCCCC)=O
InChi Code
InChI=1S/C39H68O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(41)43-36-37(35-40)44-39(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h11-14,17-20,37,40H,3-10,15-16,21-36H2,1-2H3/b13-11-,14-12-,19-17-,20-18-/t37-/m0/s1
InChi Key
MQGBAQLIFKSMEM-ZHARMHCNSA-N
Side Chain Carbon Sum
36:4
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    10 mg

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    50 mg

    $218

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    Product Description

    1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (Item No. 90150) (18:2) side chains attached at both the sn-1 and sn-2 positions. It has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes.1,2 1,2-Dilinoleoyl-sn-glycerol is upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rustow, B., Schlame, M., Rabe, H., et al. Species pattern of phosphatidic acid, diacylglycerol, CDP-diacylglycerol and phosphatidylglycerol synthesized de novo in rat liver mitochondria. Biochim. Biophys. Acta 1002(2), 261-263 (1989).

    2. Maréchal, E., Block, M.A., Joyard, J., et al. Comparison of the kinetic properties of MGDG synthase in mixed micelles and in envelope membranes from spinach chloroplast. FEBS Lett. 352(3), 307-310 (1994).

    3. Kenny, L., Baker, P.N., and Broadhurst, D. Detection risk of pre-eclampsia. (2016).