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Unlabeled Version(s)
10012592Lacosamide
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Lacosamide-d3

Item No. 25426

Restricted Product (Schedule V)
Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Harkoseride-d3
Technical Information
Formal Name
2R-(acetylamino)-3-(methoxy-d3)-N-(phenylmethyl)-propanamide
CAS Number
1217689-95-6
Molecular Formula
C13H15D3N2O3
Formula Weight
253.3
Purity
≥99% deuterated forms (d1-d3)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: SolubleMethanol: Soluble
SMILES
O=C([C@H](NC(C)=O)COC([2H])([2H])[2H])NCC1=CC=CC=C1
InChi Code
InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1/i2D3
InChi Key
VPPJLAIAVCUEMN-IBIJPGRPSA-N
Regulatory Information
DEA Schedule
V
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Lacosamide-d3 (Item No. 25426) is intended for use as an internal standard for the quantification of lacosamide (Item No. 10012592) by GC- or LC-MS. Lacosamide is categorized as an anticonvulsant.1,2,3 Formulations containing lacosamide have been used in the treatment of partial-onset and tonic-clonic seizures. Lacosamide-d3 is regulated as a Schedule V compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Luszczki, J.J. Third-generation antiepileptic drugs: Mechanisms of action, pharmacokinetics and interactions. Pharmacol. Rep. 61(2), 197-216 (2009).

    2. Brandt, C., Heile, A., Potschka, H., et al. Effects of the novel antiepileptic drug lacosamide on the dvelopment of amygdala kindling in rats. Epilepsia 47(11), (2006).

    3. Stöhr, T., Kupferberg, H.J., Stables, J.P., et al. Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy. Epilepsy Res. 74(2-3), 147-154 (2007).