An internal standard for the quantification of warfarin
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Unlabeled Version(s)
13566(±)-Warfarin
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(±)-Warfarin-d5

Item No. 25432

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-hydroxy-3-[3-oxo-1-(phenyl-d5)butyl]-2H-1-benzopyran-2-one
CAS Number
75472-93-4
Molecular Formula
C19H11D5O4
Formula Weight
313.4
Purity
≥99% deuterated forms (d1-d5)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 25 mg/mlEthanol: 5 mg/ml
SMILES
O=C1OC2=CC=CC=C2C(O)=C1C(C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])CC(C)=O
InChi Code
InChI=1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3/i2D,3D,4D,7D,8D
InChi Key
PJVWKTKQMONHTI-ATTUOBAHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $199

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    1 mg

    $299

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    Product Description

    (±)-Warfarin-d5 is intended for use as an internal standard for the quantification of warfarin by GC- or LC-MS. (±)-Warfarin (Item No. 13566) is a vitamin K antagonist, a coumarin derivative, and a racemic mixture of (+)-warfarin (Item No. 13526) and (–)-warfarin (Item No. 13531).1,2 It is an anticoagulant that interferes with the interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting.1 Formulations containing warfarin have been used to treat and prevent blood clots in atrial fibrillation, heart valve replacement, venous thrombosis, and pulmonary embolism.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hirsh, J., Fuster, V., Ansell, J., et al. American heart association/american college of cardiology foundation guide to warfarin therapy. J. Am. Coll. Cardiol. 41(9), 1633-1652 (2003).

    2. Ufer, M. Comparative pharmacokinetics of vitamin K antagonists warfarin, phenprocoumon and acenocoumarol. Clin. Pharmacokinet. 44(12), 1227-1246 (2005).