An internal standard for the quantification of 7β-hydroxy cholesterol
Related Products
Isomer(s)
255477α-hydroxy Cholesterol-d7
Unlabeled Version(s)
200997β-hydroxy Cholesterol
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

7β-hydroxy Cholesterol-d7

Item No. 25548

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,7β)-cholest-5-ene-25,26,26,26,27,27,27-d7-3,7-diol
CAS Number
349553-97-5
Molecular Formula
C27H39D7O2
Formula Weight
409.7
Purity
≥99% deuterated forms (d1-d7)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 0.1 mg/mlEthanol: 20 mg/ml
SMILES
O[C@H](C1)CC[C@@]2(C)C1=C[C@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H]
InChi Code
InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,24+,25+,26+,27-/m1/s1/i1D3,2D3,17D
InChi Key
OYXZMSRRJOYLLO-SVAMASIOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 µg

    $222

    Add

    1 mg

    $399

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    7β-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7β-hydroxy cholesterol by GC- or LC-MS. 7β-hydroxy Cholesterol is an oxysterol formed by enzymatic and non-enzymatic oxidation of cholesterol.1 It is the primary oxysterol found in LDL and induces apoptosis and cell death of human umbilical vein endothelial cells (HUVECs) in vitro in a concentration-dependent manner. Increased plasma levels of 7β-hydroxy cholesterol positively correlate with mortality in coronary heart disease in human males.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lizard, G., Monier, S., Cordelet, C., et al. Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7β-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall. Arterioscler. Thromb. Vasc. Biol. 19(5), 1190-1200 (1999).

    2. Ziedén, B., Kaminskas, A., Kristenson, M., et al. Increased plasma 7 β-hydroxycholesterol concentrations in a population with a high risk for cardiovascular disease. Artioscler. Thromb. Vasc. Biol. 19(4), 967-971 (1999).