A synthetic phospholipid
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1,2-Dihexanoyl-sn-glycero-3-PC

Item No. 25585

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-hydroxy-N,N,N-trimethyl-10-oxo-7R-[(1-oxohexyl)oxy]-3,5,9-trioxa-4-phosphapentadecan-1-aminium, inner salt, 4-oxide
CAS Number
34506-67-7
Synonyms
  • DHPC-C6
  • L-1,2-Dihexanoyllecithin
  • 1,2-Dihexanoyl-sn-glycero-3-Phosphocholine
Molecular Formula
C20H40NO8P
Formula Weight
453.5
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: > 20 mg/mlDMSO: > 7 mg/mlEthanol: > 30 mg/mlPBS (pH 7.2): > 250 µg/ml
SMILES
[O-]P(OC[C@H](OC(CCCCC)=O)COC(CCCCC)=O)(OCC[N+](C)(C)C)=O
InChi Code
InChI=1S/C20H40NO8P/c1-6-8-10-12-19(22)26-16-18(29-20(23)13-11-9-7-2)17-28-30(24,25)27-15-14-21(3,4)5/h18H,6-17H2,1-5H3/t18-/m1/s1
InChi Key
DVZARZBAWHITHR-GOSISDBHSA-N
Side Chain Carbon Sum
12:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $88

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    50 mg

    $115

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    100 mg

    $194

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    250 mg

    $352

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    Cayman Chemical
    Learn More About Leveraging Helper Lipids to Achieve Versatile LNPs
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    Product Description

    1,2-Dihexanoyl-sn-glycero-3-PC (DHPC-C6) is a synthetic phospholipid containing the short-chain (6:0) caproic acid inserted at the sn-1 and sn-2 positions. It is a substrate for phospholipase C isolated from B. cereus as well as phospholipase A2 isolated from A. halys blomhoffi and N. naja atra snake venom.1,2 DHPC is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Little, C. Phospholipase C from Bacillus cereus. Action on some artificial lecithins. Acta Chem. Scand. B 31(4), 267-272 (1977).

    2. Teshima, K., Kitagawa, Y., Samejima, Y., et al. Role of Ca2+ in the substrate binding and catalytic functions of snake venom phospholipases A2. J. Biochem. 106(3), 518-527 (1989).

    3. Batenjany, M.M., O'Leary, T.J., Levin, I.W., et al. Packing characteristics of two-component bilayers composed of ester- and ether-linked phospholipids. Biophys. J. 72(4), 1695-1700 (1997).