A lysophospholipid
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1-Stearoyl-2-hydroxy-sn-glycero-3-PE

Item No. 25593

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
octadecanoic acid, (2R)-3-[[(2-aminoethoxy)hydroxyphosphinyl]oxy]-2-hydroxypropyl ester
CAS Number
69747-55-3
Synonyms
  • 18:0 LPE
  • 18:0 Lyso-PE
  • 1-Octadecanoyl-sn-glycero-3-phosphoethanolamine
  • 1-Stearoyl-2-hydroxy-sn-glycero-3-phosphatidylethanolamine
  • 1-Stearoyl lyso-PE
  • 1-Stearoyl LPE
Molecular Formula
C23H48NO7P
Formula Weight
481.6
Purity
≥95% (9:1 mixture of 1-acyl and 2-acyl)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly soluble
SMILES
O[C@@H](COP(OCC[NH3+])([O-])=O)COC(CCCCCCCCCCCCCCCCC)=O
InChi Code
InChI=1S/C23H48NO7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(26)29-20-22(25)21-31-32(27,28)30-19-18-24/h22,25H,2-21,24H2,1H3,(H,27,28)/t22-/m1/s1
InChi Key
BBYWOYAFBUOUFP-JOCHJYFZSA-N
Side Chain Carbon Sum
18:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $108

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    10 mg

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    25 mg

    $270

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    Cayman Chemical
    Learn More About Leveraging Helper Lipids to Achieve Versatile LNPs
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    Product Description

    1-Stearoyl-2-hydroxy-sn-glycero-3-PE is a lysophospholipid.1 It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) receptor antagonist AM095 (Item No. 22141).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lee, J.M., Park, S.J., and Im, D.S. Lysophosphatidylethanolamine increases intracellular Ca2+ through LPA1 in PC-12 neuronal cells. Biochem. Biophys. Res. Commun. 461(2), 378-382 (2015).