A carbamate insecticide
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Labeled Version(s)
39558Carbofuran-d3
Metabolite(s)
241463-hydroxy Carbofuran
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Carbofuran

Item No. 25635

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
7-(N-methylcarbamate) 2,3-dihydro-2,2-dimethyl-7-benzofuranol
CAS Number
1563-66-2
Synonyms
  • BAY 70143
  • NSC 167822
Molecular Formula
C12H15NO3
Formula Weight
221.3
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly solubleMethanol: Heated
SMILES
CC1(C)OC2=C(OC(NC)=O)C=CC=C2C1
InChi Code
InChI=1S/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)
InChi Key
DUEPRVBVGDRKAG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

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    100 mg

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    Product Description

    Carbofuran is a carbamate insecticide that inhibits acetylcholinesterase (AChE) in insects and mammals (Kas = 9.4, 30, and 210 µM for M. domestica brain, A. mellifera brain, and bovine erythrocyte AChE, respectively).1 It also inhibits AChE from rat and human erythrocytes with IC50 values of 40 and 25 nM, respectively.2 It is toxic to the housefly M. domestica (LD50 = 4.6 mg/kg) and fourth-instar larvae of the mosquito C. pipiens with an LC50 value of 0.054 ppm. Carbofuran is toxic to birds, rats (LD50 = 4-11 mg/kg), and other mammals including dogs, sheep, and cattle, and is considered an environmental toxin.1,3 Formulations containing carbofuran have been used in agriculture for the control of insects, nematodes, mites, and ticks.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yu, C., Metcalf, R.L., and Booth, G.M. Inhibition of acetylcholinesterase from mammals and insects by carbofuran and its related compounds and their toxicities toward these animals. J. Agric. Food Chem. 20(5), 923-926 (1972).

    2. Rao, P.S., Roberts, G.H., Pope, C.N., et al. Comparative inhibition of rodent and human erythrocyte acetylcholinesterase by carbofuran and carbaryl. Pestic. Biochem. Physiol. 48(2), 79-84 (1994).

    3. Gupta, R.C. Carbofuran toxicity. J. Toxicol. Environ. Health 43(4), 383-418 (1994).