A synthetic phospholipid
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Dihexadecyl Phosphate

Item No. 25727

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-hexadecanol, 1,1'-(hydrogen phosphate)
CAS Number
2197-63-9
Synonyms
  • Dicetyl Phosphate
  • NSC 12429
Molecular Formula
C32H67O4P
Formula Weight
546.8
Purity
≥90%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly soluble
SMILES
O=P(OCCCCCCCCCCCCCCCC)(O)OCCCCCCCCCCCCCCCC
InChi Code
InChI=1S/C32H67O4P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35-37(33,34)36-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-32H2,1-2H3,(H,33,34)
InChi Key
RNPXCFINMKSQPQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 g

    $72

    Add

    5 g

    $286

    Add

    10 g

    $429

    Add

    25 g

    $715

    Add
    Cayman Chemical
    Learn More About Leveraging Helper Lipids to Achieve Versatile LNPs
    READ THE ARTICLE
    Product Description

    Dihexadecyl phosphate is a negatively-charged synthetic phospholipid that has been used to impart a negative charge to neutral liposomes.1 It has also been used in the generation of micelles, liposomes, and other types of artificial membranes, including niosomes for drug delivery.2,3 Formulations containing dihexadecyl phosphate have been used as emulsifying agents in cosmetics.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mortara, R.A., Quina, F.H., and Chaimovich, H. Formation of closed vesicles from a simple phosphate diester. Preparation and some properties of vesicles of dihexadecyl phosphate. Biochem. Biophys. Res. Commun. 81(4), 1080-1086 (1978).

    2. Paradies, H.H. Bilayer structure of dihexadecyl phosphate. Biochem. Biophys. Res. Commun. 101(4), 1096-1101 (1981).

    3. Abdelbary, A.A., and AbouGhaly, M.H.H. Design and optimization of topical methotrexate loaded niosomes for enhanced management of psoriasis: Application of Box-Behnken design, in-vitro evaluation and in-vivo skin deposition study. Int. J. Pharm. 485(1-2), 235-243 (2015).