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1,2-Dierucoyl-sn-glycero-3-PC (DEPC) is a phospholipid containing erucic acid (docosenoic acid; Item No. 90175) at the sn-1 and sn-2 positions. It has been used in the study of lipid membranes and to determine the effect of long-chain phospholipids on the secondary structure of human islet amyloid polypeptide (hIAPP).1,2,3
WARNING This product is not for human or veterinary use.
1. Structural determinants of water permeability through the lipid membrane. J. Gen. Physiol. 131(1), 69-76 (2008).
2. Interaction of lipids with the neurotensin receptor 1. Biochim. Biophys. Acta 1858(6), 1278-1287 (2016).
3. Phospholipids critical micellar concentrations trigger different mechanisms of intrinsically disordered proteins interaction with model membranes. J. Phys. Chem. Lett. 9(17), 5125-5129 (2018).