An organofluorine acaricide
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Etoxazole

Item No. 25782

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(2,6-difluorophenyl)-4-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-oxazole
CAS Number
153233-91-1
Molecular Formula
C21H23F2NO2
Formula Weight
359.4
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly soluble
SMILES
CC(C)(C)C1=CC=C(C2N=C(C3=C(F)C=CC=C3F)OC2)C(OCC)=C1
InChi Code
InChI=1S/C21H23F2NO2/c1-5-25-18-11-13(21(2,3)4)9-10-14(18)17-12-26-20(24-17)19-15(22)7-6-8-16(19)23/h6-11,17H,5,12H2,1-4H3
InChi Key
IXSZQYVWNJNRAL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $53

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    50 mg

    $98

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    100 mg

    $185

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    Cayman Chemical
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    Product Description

    Etoxazole is an organofluorine acaricide.1,2 It induces toxicity in two-spotted spider mite (T. urticae) larvae (LC50 = 0.036 mg/L for the London reference strain) through inhibition of chitin synthase 1. It reduces acetylcholinesterase (AChE) activity in the freshwater fish O. niloticus in a concentration-dependent manner.3 Etoxazole (2.2-22 mg/kg per day) inhibits the activity of catalase, glutathione peroxidase (GPX), and AChE in the liver and kidneys of rats in a dose-dependent manner.2 Formulations containing etoxazole have been used for the control of mites in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Demaeght, P., Osborne, E.J., Odman-Maresh, J., et al. High resolution genetic mapping uncovers chitin synthase-1 as the target-site of the structurally diverse mite growth inhibitors clofentezine, hexythiazox and etoxazole in Tetranychus urticae. Insect Biochem. Mol. Biol. 51, 52-61 (2014).

    2. Yilmaz, M., Rencuzogullari, E., and Canli, M. Investigations on the effects of etoxazole in the liver and kidney of Wistar rats. Environ. Sci. Pollut. Res. Int. 24(24), 19635-19639 (2017).

    3. Sevgiler, Y., Oruç, E.O., and Üner, N. Evaluation of etoxazole toxicity in the liver of Oreochromis niloticus. Pestic. Biochem. Physiol. 78(1), 1-8 (2004).