An ω-5 long-chain polyunsaturated fatty acid
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Isomer(s)
22976β-Eleostearic Acid
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9(Z),11(E),13(Z)-Octadecatrienoic Acid

Item No. 26057

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9Z,11E,13Z-octadecatrienoic acid
CAS Number
544-72-9
Synonyms
  • FA 18:3
  • Punicic Acid
  • Trichosanic Acid
Molecular Formula
C18H30O2
Formula Weight
278.4
Purity
≥95%
Formulation
A solution in methanol
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 10 mg/mlEthanol: 20 mg/ml
λmax
264, 274, 286 nm
SMILES
CCCC/C=C\C=C\C=C/CCCCCCCC(O)=O
InChi Code
InChI=1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h5-10H,2-4,11-17H2,1H3,(H,19,20)/b6-5-,8-7+,10-9-
InChi Key
CUXYLFPMQMFGPL-BGDVVUGTSA-N
Side Chain Carbon Sum
18:3
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

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    5 mg

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    10 mg

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    Product Description

    9(Z),11(E),13(Z)-Octadecatrienoic acid is an ω-5 long-chain polyunsaturated fatty acid and an isomer of 9(E),11(E),13(E)-octadecatrienoic acid (Item No. 22976) and of conjugated linoleic acids.1 It has been found as a major component in pomegranate seed oil, making up approximately 65% of the fatty acid content.2 9(Z),11(E),13(Z)-Octadecatrienoic acid binds to the ligand-dependent transactivation domain (AF2) of PPARγ (IC50 = 2.5 µM) and increases PPARα and PPARγ activity in 3T3-L1 cells in a reporter assay.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hontecillas, R., O'Shea, M., Einerhand, A., et al. Activation of PPARγ and α by punicic acid ameliorates glucose tolerance and suppresses obesity-related inflammation. J. Am. Coll. Nutr. 28(2), 184-195 (2009).

    2. Schubert, S.Y., Lansky, E.P., and Neeman, I. Antioxidant and eicosanoid enzyme inhibition properties of pomegranate seed oil and fermented juice flavonoids. J. Ethnopharmacol. 66(1), 11-17 (1999).

    Product Citations

    Zhang, L.J., Salekeen, R., Soto-Palma, C., et al. Article polyunsaturated lipid senolytics exploit a ferroptotic vulnerability in senescent cells. Cell Press Blue 1(1), 100004 (2026).