A goitrogen
Related Products
Isomer(s)
35620Epigoitrin
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Product Categories

Product Type

Biochemicals
Natural Products

(±)-Goitrin

Item No. 26382

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-ethenyl-2-oxazolidinethione
CAS Number
13190-34-6
Synonyms
  • DL-Goitrin
  • (R,S)-Goitrin
Molecular Formula
C5H7NOS
Formula Weight
129.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
λmax
246 nm
SMILES
S=C1OC(C=C)CN1
InChi Code
InChI=1S/C5H7NOS/c1-2-4-3-6-5(8)7-4/h2,4H,1,3H2,(H,6,8)
InChi Key
UZQVYLOFLQICCT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 mg

    $222

    Add

    50 mg

    $266

    Add

    100 mg

    $442

    Add
    Product Description

    (±)-Goitrin is a goitrogen and antithyroid compound that has been found in plants of the Brassica family.1,2 Dietary administration of (±)-goitrin (0.06-0.18% w/w) increases thyroid weight and decreases thyroid radioactive iodine uptake in rats fed a low-iodine diet.1 It also increases thyroid weight in chicks in a dose-dependent manner.2 (±)-Goitrin inhibits norepinephrine formation by bovine dopamine-β-hydroxylase in vitro when used at a concentration of 0.2 mM.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Faiman, C., Ryan, R.J., and Eichel, H.J. Effect of goitrin analogues and related compounds on the rat thyroid gland. Endocrinology 81(1), 88-92 (1967).

    2. Akiba, Y., and Matsumoto, J. Antithyroid activity of goitrin in chicks. Poult. Sci. 55(2), 716-719 (1976).

    3. Zenker, N., Hubbard, L.S., and Wright, J. Inhibition of dopamine β-hydroxylase by goitrin, a natural antithyroid compound. J. Nat. Prod. 51(5), 862-865 (1988).