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Codeine (phosphate hydrate)

Item No. 26514

Restricted Product (Schedule II)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Codicept
  • Coducept
  • Methylmorphine
  • Morphine 3-methyl ether
Technical Information
Formal Name
(5α,6α)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-morphinan-6-ol, phosphate, hydrate (2:2:1)
CAS Number
41444-62-6
Molecular Formula
C18H21NO3 • H3PO4 [1/2H2O]
Formula Weight
406.4
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 10 mg/ml
λmax
212 nm
SMILES
O[C@@H](C=C[C@@]1([H])[C@H]2CC3=CC=C4OC)[C@@]5([H])[C@]1(CCN2C)C3=C4O5.OP(O)(O)=O.O
InChi Code
InChI=1S/2C18H21NO3.2H3O4P.H2O/c2*1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;2*1-5(2,3)4;/h2*3-6,11-13,17,20H,7-9H2,1-2H3;2*(H3,1,2,3,4);1H2/t2*11-,12+,13-,17-,18-;;;/m00.../s1
InChi Key
DKSZLDSPXIWGFO-BLOJGBSASA-N
Regulatory Information
DEA Schedule
II
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Codeine (phosphate hydrate) (Item No. 26514) is an analytical reference standard categorized as an opioid.1 Codeine is an analgesic and formulations containing it have commonly been abused.2 Codeine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Codd, E.E., Shank, R.P., Schupsky, J.J., et al. Serotonin and norepinephrine uptake inhibiting activity of centrally acting analgesics: Structural determinants and role in antinociception. J. Pharmacol. Exp. Ther. 274(3), 1263-1270 (1995).

    2. Cone, E.J., Darwin, W.D., and Buchwald, W.F. Assay for codeine, morphine and ten potential urinary metabolites by gas chromatography--mass fragmentography. J. Chromatogr. 275(2), 307-318 (1983).