A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Possession of a DEA Controlled Substance registration is not necessary nor is a DEA 222 form required to purchase this product
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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Hydrocodone (CRM)

A 1 mg/ml solution in methanol

Item No. ISO60144

Exempt Product (US)
Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Dihydrocodeinone
  • (–)-Hydrocodone
  • NSC 19044
Technical Information
Formal Name
4,5α-epoxy-3-methoxy-17-methyl-morphinan-6-one
CAS Number
125-29-1
Molecular Formula
C18H21NO3
Formula Weight
299.4
Formulation
A 1 mg/ml solution in methanol
SMILES
CN1[C@H]2[C@@]3([H])[C@]4(CC1)[C@](OC5=C4C(C2)=CC=C5OC)([H])C(CC3)=O
InChi Code
InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-12,17H,4-5,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1
InChi Key
LLPOLZWFYMWNKH-CMKMFDCUSA-N
Regulatory Information
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - does not require DEA Controlled Substance registration or DEA 222 form. For alternate sizes please contact sales.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

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    Product Description

    Hydrocodone (CRM) (Item No. ISO60144) is a certified reference material categorized as an opioid.1,2 It is a metabolite of codeine (Item No. ISO60140).3 Like other opioid analgesics, hydrocodone is commonly abused.4 Hydrocodone is regulated as a Schedule II compound in the United States. Hydrocodone (CRM) (Item No. ISO60144) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Trescot, A.M., Datta, S., Lee, M., et al. Opioid pharmacology. Pain Physician 11(2 Suppl.), S133-S153 (2008).

    2. Codd, E.E., Shank, R.P., Schupsky, J.J., et al. Serotonin and norepinephrine uptake inhibiting activity of centrally acting analgesics: Structural determinants and role in antinociception. J. Pharmacol. Exp. Ther. 274(3), 1263-1270 (1995).

    3. Oyler, J.M., Cone, E.J., Joseph, R.E., Jr., et al. Identification of hydrocodone in human urine following controlled codeine administration. J. Anal. Toxicol. 24(7), 530-535 (2000).

    4. Atluri, S.A., Sudarshan, G., and Manchikanti, L. Assessment of the trends in medical use and misuse of opioid analgesics from 2004 to 2011. Pain Physician 17(2), E119-E128 (2014).