A phytosterol
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Campestanol

Item No. 26538

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,5α,24R)-ergostan-3-ol
CAS Number
474-60-2
Synonyms
  • 24-Methyl-5α-cholestan-3β-ol
Molecular Formula
C28H50O
Formula Weight
402.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: slightly soluble
SMILES
C[C@H](CC[C@@H](C)C(C)C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
InChi Code
InChI=1S/C28H50O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h18-26,29H,7-17H2,1-6H3/t19-,20-,21+,22+,23+,24-,25+,26+,27+,28-/m1/s1
InChi Key
ARYTXMNEANMLMU-ATEDBJNTSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $236

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    1 mg

    $423

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    Product Description

    Campestanol is a phytosterol found in vegetables, fruits, nuts, and seeds.1 Dietary administration of vegetable stanol esters (1% w/w) containing campestanol (30.1%) and sitostanol (65.7%; Item No. 26094) lower serum cholesterol, LDL, VLDL, and intermediate-density lipoprotein (IDL) cholesterol levels in an APOE*3-Leiden transgenic mouse model of atherosclerosis.2 This combination of campestanol with sitostanol also reduces atherosclerotic lesion area by 91% and the proportion of lesions with extensive macrophage infiltration.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gylling, H., and Miettinen, T.A. Cholesterol reduction by different plant stanol mixtures and with variable fat intake. Metabolism 48(5), 575-580 (1999).

    2. Volger, O.L., Mensink, R.P., Plat, J., et al. Dietary vegetable oil and wood derived plant stanol esters reduce atherosclerotic lesion size and severity in apoE*3-Leiden transgenic mice. Atherosclerosis 157(2), 375-381 (2001).