An internal standard for the quantification of carnitine
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DL-Carnitine-d9 (chloride)

Item No. 26566

Technical Information
Formal Name
3-carboxy-2-hydroxy-N,N,N-tri(methyl-d3)-1-propanaminium, monochloride
CAS Number
1219386-75-0
Synonyms
  • (±)-Carnitine-d9
Molecular Formula
C7H7D9NO3 • Cl
Formula Weight
Purity
≥99% deuterated forms (d1-d9)
A crystalline solid
DMF: 15 mg/mlDMSO: 20 mg/mlEthanol: 25 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
OC(CC(O)C[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O.[Cl-]
InChi Code
InChI=1S/C7H15NO3.ClH/c1-8(2,3)5-6(9)4-7(10)11;/h6,9H,4-5H2,1-3H3;1H/i1D3,2D3,3D3;
InChi Key
JXXCENBLGFBQJM-KYRNGWDOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    DL-Carnitine-d9 is intended for use as an internal standard for the quantification of carnitine (Item Nos. 21489 | 16749) by GC- or LC-MS. DL-Carnitine is a racemic mixture of L- and D-carnitine. Unlike L-carnitine, DL-carnitine (60 and 120 µM) does not increase glucose or urea production from L-glutamine (Item No. 23716) in isolated rat liver and does not compensate for carnitine deficiency in the skeletal muscle of rats receiving a carnitine-deficient diet.1,2 DL-Carnitine induces tetanic fade in stimulated isolated rat phrenic nerve diaphragm preparations when used at a concentration of 60 µM, an effect that can be blocked by choline.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lopes, G., Gazola, V.A., Galende, S.B., et alComparative acute effects of l-carnitine and dl-carnitine on hepatic catabolism of l-alanine and l-glutamine in rats. Acta Pharmacol. Sin. 25(10), 1257-1261 (2004).

    2. Spasov, A.A., Iezhitsa, I.N., Kravchenko, M.S., et alEffects of L-, D-, and DL-carnitine on morphometric parameters of skeletal muscle and exercise performance of laboratory animals receiving carnitine-deficient diet. Bull. Exp. Biol. Med. 142(4), 458-460 (2006).

    3. Lopes, G., Bazotte, R.B., Curi, R., et alL- and DL-carnitine induce tetanic fade in rat neuromuscular preparation. Braz. J. Med. Biol. Res. 36(9), 1255-1262 (2003).