An internal standard for the quantification of oleoyl-L-carnitine
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Oleoyl-L-carnitine-d3 (chloride)

Item No. 26578

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(R)-3-carboxy-N,N-dimethyl-N-(methyl-d3)-2-(oleoyloxy)propan-1-aminium, monochloride
Synonyms
  • CAR 18:1-d3
  • C18:1 Carnitine-d3
  • L-Carnitine octadecanoyl ester-d3
  • L-Carnitine oleoyl ester-d3
  • Octadecanoyl-L-carnitine-d3
  • L-Octadecanoylcarnitine-d3
  • L-Oleoylcarnitine-d3
Molecular Formula
C25H45D3NO4 • Cl
Formula Weight
465.1
Purity
≥99% deuterated forms (d1-d3)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 14 mg/mlEthanol: 20 mg/ml
SMILES
OC(C[C@H](C[N+](C([2H])([2H])[2H])(C)C)OC(CCCCCCC/C=C\CCCCCCCC)=O)=O.[Cl-]
InChi Code
InChI=1S/C25H47NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-25(29)30-23(21-24(27)28)22-26(2,3)4;/h12-13,23H,5-11,14-22H2,1-4H3;1H/b13-12-;/t23-;/m1./s1/i2D3;
InChi Key
JPDKUMDAMZLOJR-CQZOHPAWSA-N
Side Chain Carbon Sum
18:1
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $124

    Add

    5 mg

    $490

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    Oleoyl-L-carnitine-d3 is intended for use as an internal standard for the quantification of oleoyl-L-carnitine (Item Nos. 26557 | 39014) by GC- or LC-MS. Oleoyl-L-carnitine is a long-chain acylcarnitine and an inhibitor of glycine transporter 2 (GlyT2; IC50 = 340 nM).1,2 It is selective for GlyT2 over GlyT1 (IC50 = >10,000 nM). Plasma levels of oleoyl-L-carnitine are increased in patients with chronic kidney disease or end-stage renal disease receiving incident hemodialysis and these are associated with cardiovascular mortality.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kalim, S., Clish, C.B., Wenger, J., et al. A plasma long-chain acylcarnitine predicts cardiovascular mortality in incident dialysis patients. J. Am. Heart Assoc. 2(6), e000542 (2013).

    2. Carland, J.E., Mansfield, R.E., Ryan, R.M., et al. Oleoyl-L-carnitine inhibits glycine transport by GlyT2. Br. J. Pharmacol. 168(4), 891-902 (2013).