A sesquiterpene
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Curcumenol

Item No. 26715

Technical Information
Formal Name
(3S,3aS,6R,8aS)-1,2,3,4,5,8a-hexahydro-3,8-dimethyl-5-(1-methylethylidene)-6H-3a,6-epoxyazulen-6-ol
CAS Number
19431-84-6
Synonyms
  • (+)-Curcumenol
Molecular Formula
C15H22O2
Formula Weight
Purity
≥98%
A crystalline solid
DMF: 10 mg/mlDMSO: 5 mg/mlEthanol: 3 mg/mlPBS (pH 7.2): 0.3 mg/ml
λmax
262 nm
SMILES
CC([C@@]1([H])[C@]([C@@H](C)CC1)(O2)C/3)=C[C@]2(O)C3=C(C)/C
InChi Code
InChI=1S/C15H22O2/c1-9(2)13-8-14-11(4)5-6-12(14)10(3)7-15(13,16)17-14/h7,11-12,16H,5-6,8H2,1-4H3/t11-,12-,14-,15+/m0/s1
InChi Key
ISFMXVMWEWLJGJ-NZBPQXDJSA-N
Origin
Plant/Curcumae Rhizoma
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Curcumenol is a sesquiterpene that has been found in Curcuma species.1,2 It is active against methicillin-resistant S. aureus (MRSA) and P. aeruginosa and cytotoxic to CEM-SS lymphoblastic leukemia cells (IC50 = 11.9 µg/ml).1 It also decreases cell viability of AGS human gastric carcinoma cells (IC50 = 263.34 µM).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aspollah Sukari, M., Wah, T.S., Saad, S.M., et alBioactive sesquiterpenes from Curcuma ochrorhiza and Curcuma heyneana. Nat. Prod. Res. 24(9), 838-845 (2010).

    2. Lee, T.K., Lee, D., Lee, S.R., et alSesquiterpenes from Curcuma zedoaria rhizomes and their cytotoxicity against human gastric cancer AGS cells. Bioorg. Chem. 87, 117-122 (2019).