An internal standard for the quantification of ω-MCA
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ω-Muricholic Acid-d4

Item No. 27037

Technical Information
Formal Name
(3α,5β,6α,7β)-3,6,7-trihydroxy-cholan-24-oic-2,2,4,4-d4 acid
Synonyms
  • ω-MCA-d4
Molecular Formula
C24H36D4O5
Formula Weight
Purity
≥99% deuterated forms (d1-d4)
A crystalline solid
DMF: 30 mg/mlDMF:PBS (pH 7.2) (1:1): 0.5mg/mlDMSO: 20 mg/mlEthanol: 20 mg/ml
SMILES
C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)[C@H](O)[C@]4([H])C([2H])([2H])[C@H](O)C([2H])([2H])C[C@]4(C)[C@@]3([H])CC[C@@]21C
InChi Code
InChI=1S/C24H40O5/c1-13(4-7-19(26)27)15-5-6-16-20-17(9-11-23(15,16)2)24(3)10-8-14(25)12-18(24)21(28)22(20)29/h13-18,20-22,25,28-29H,4-12H2,1-3H3,(H,26,27)/t13-,14-,15-,16+,17+,18+,20+,21-,22-,23-,24-/m1/s1/i8D2,12D2
InChi Key
DKPMWHFRUGMUKF-QYMYDAHASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    ω-Muricholic acid-d4 (ω-MCA-d4) is intended for use as an internal standard for the quantification of ω-MCA (Item No. 20292) by GC- or LC-MS. ω-MCA is a murine-specific secondary bile acid.1,2 It is formed via enzymatic conversion of β-MCA (Item No. 20287) by a variety of intestinal microorganisms, including Clostridium, in rat and mouse gut.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Eyssen, H., De Pauw, G., Stragier, J., et alCooperative formation of ω-muricholic acid by intestinal microorganisms. Appl. Environ. Microbiol. 45(1), 141-147 (1983).

    2. Sacquet, E.C., Raibaud, P.M., Mejean, C., et alBacterial formation of ω-muricholic acid in rats. Appl. Environ. Microbiol. 37(6), 1127-1131 (1979).