A racemic mixture of (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol
Related Products
Isomer(s)
30097(+)-N-3-Benzylnirvanol
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(±)-N-3-Benzylnirvanol

Item No. 27298

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-ethyl-5-phenyl-3-(phenylmethyl)-2,4-imidazolidinedione
CAS Number
93879-40-4
Molecular Formula
C18H18N2O2
Formula Weight
294.4
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly SolubleMethanol: Slightly Soluble
SMILES
O=C(N1CC2=CC=CC=C2)C(C3=CC=CC=C3)(CC)NC1=O
InChi Code
InChI=1S/C18H18N2O2/c1-2-18(15-11-7-4-8-12-15)16(21)20(17(22)19-18)13-14-9-5-3-6-10-14/h3-12H,2,13H2,1H3,(H,19,22)
InChi Key
ZMZDHUHMXXALFX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $41

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    5 mg

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    10 mg

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    Product Description

    (±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol.1,2 (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol are inhibitors of the cytochrome P450 (CYP) isoform CYP2C19 (Kis = 0.25 and 5.3 μM, respectively).1 (±)-N-3-Benzylnirvanol (20 mg/kg, i.p.) lowers plasma levels of cholesterol in mice.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Suzuki, H., Kneller, M.B., Haining, R.L., et al. (+)-N-3-Benzyl-nirvanol and (−)-N-3-benzyl-phenobarbital: New potent and selective in vitro inhibitors of CYP2C19. Drug Metab. Dispos. 30(3), 235-239 (2002).

    2. Maguire, J.H., Murthy, A.R., and Hall, I.H. Hypolipidemic activity of antiepileptic 5-phenylhydantoins in mice. Eur. J. Pharmacol. 117(1), 135-138 (1985).