An Analytical Reference Standard
Related Products
Labeled Version(s)
27811(±)-Baclofen-d4
Research Tool(s)
18600(±)-Baclofen
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(±)-Baclofen

Item No. 27326

Technical Information
Formal Name
β-(aminomethyl)-4-chloro-benzenepropanoic acid
CAS Number
1134-47-0
Molecular Formula
C10H12ClNO2
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
DMF: Partially solubleDMSO: Partially solubleEthanol: Partially solublePBS (pH 7.2): 0.5 mg/ml
λmax
258, 318, 332 nm
SMILES
ClC1=CC=C(C(CN)CC(O)=O)C=C1
InChi Code
InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
InChi Key
KPYSYYIEGFHWSV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    (±)-Baclofen (Item No. 27326) is an analytical reference standard categorized as a gabapentinoid and a nootropic.1,2 (±)-Baclofen also has analgesic, skeletal muscle relaxant, and sedative properties.3,4 Formulations containing (±)-baclofen have been used in the treatment of spasticity in patients with multiple sclerosis or spinal cord injuries. This product is intended for use in analytical forensic applications. This product is also available as a general research tool (Item No. 18600).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bowery, N.G., Hill, D.R., and Hudson, A.L. Characteristics of GABAB receptor binding sites on rat whole brain synaptic membranes. Br. J. Pharmacol. 78(1), 191-206 (1983).

    2. Tyurenkov, I.N., Borodkina, L.E., Bagmetova, V.V., et alComparison of nootropic and neuroprotective features of aryl-substituted analogs of gamma-aminobutyric acid. Bull. Exp. Biol. Med. 160(4), 465-469 (2016).

    3. Chou, R., Peterson, K., and Helfand, M. Comparative efficacy and safety of skeletal muscle relaxants for spasticity and musculoskeletal conditions: A systematic review. J. Pain Symptom Manage. 28(2), 140-175 (2004).

    4. de Beaurepaire, R., Sinclair, J.M.A., Heydtmann, M., et alThe use of baclofen as a treatment for alcohol use disorder: A clinical practice perspective. Front. Psychiatry 9, 708 (2019).