A pentose sugar alcohol
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Ribitol

Item No. 27362

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
488-81-3
Synonyms
  • Adonitol
  • NSC 16868
Molecular Formula
C5H12O5
Formula Weight
152.1
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5mg/mLDMSO: 25mg/mLPBS (pH 7.2): 5mg/mL
SMILES
OC[C@@H]([C@@H]([C@@H](CO)O)O)O
InChi Code
InChI=1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4+,5-
InChi Key
HEBKCHPVOIAQTA-ZXFHETKHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 g

    $54

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    25 g

    $120

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    50 g

    $223

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    100 g

    $418

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    Product Description

    Ribitol is a pentose sugar alcohol derived from ribose in vivo via the pentose phosphate pathway.1 It is a component of the glycopolymer teichoic acid in bacterial cell walls.2 Levels of ribitol are increased in the brain, cerebrospinal fluid, urine, and plasma of a patient with ribose-5-phosphate isomerase (RPI) deficiency, an extremely rare inborn error of metabolism characterized by a heterozygous frameshift mutation and missense allele in the RPI gene leading to leukoencephalopathy and mild peripheral polyneuropathy.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Huck, J.H.J., Verhoeven, N.M., Struys, E.A., et al. Ribose-5-phosphate isomerase deficiency: New inborn error in the pentose phosphate pathway associated with a slowly progressive leukoencephalopathy. Am. J. Hum. Genet. 74(4), 745-751 (2004).

    2. Vinogradov, E., Sadovskaya, I., Li, J., et al. Structural elucidation of the extracellular and cell-wall teichoic acids of Staphylococcus aureus MN8m, a biofilm forming strain. Carbohydr. Res. 341(6), 738-743 (2006).