A peptide fragment of preproadrenomedullin
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Product Type

Biochemicals
Peptides
Peptide Hormones

Proadrenomedullin (N-20) (rat) (trifluoroacetate salt)

Item No. 27405

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-alanyl-L-arginyl-L-leucyl-L-α-aspartyl-L-threonyl-L-seryl-L-seryl-L-glutaminyl-L-phenylalanyl-L-arginyl-L-lysyl-L-lysyl-L-tryptophyl-L-asparaginyl-L-lysyl-L-tryptophyl-L-alanyl-L-leucyl-L-seryl-L-argininamide, trifluoroacetate salt
Synonyms
  • proADM
  • ProAM
  • Mid-Regional proADM
  • Mid-Regional Proadrenomedullin
  • MR-proADM
  • MR-proAM
Molecular Formula
C111H177N37O28 • XCF3COOH
Formula Weight
2477.8
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
O=C(O)C(F)(F)F.[H]N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)C)=O)CC1=CNC2=C1C=CC=C2)=O)=O)=O)CC3=CNC4=C3C=CC=C4)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)CC(O)=O)=O)=O)=O)C
InChi Code
InChI=1S/C111H177N37O28.C2HF3O2/c1-56(2)44-75(100(168)145-82(53-149)105(173)131-68(89(118)157)33-21-41-125-109(119)120)138-91(159)59(6)130-98(166)78(47-62-51-128-66-28-13-11-26-64(62)66)141-95(163)71(32-17-20-40-114)135-103(171)80(49-86(117)154)143-102(170)79(48-63-52-129-67-29-14-12-27-65(63)67)142-94(162)70(31-16-19-39-113)134-92(160)69(30-15-18-38-112)133-93(161)73(35-23-43-127-111(123)124)136-101(169)77(46-61-24-9-8-10-25-61)140-97(165)74(36-37-85(116)153)137-106(174)83(54-150)146-107(175)84(55-151)147-108(176)88(60(7)152)148-104(172)81(50-87(155)156)144-99(167)76(45-57(3)4)139-96(164)72(132-90(158)58(5)115)34-22-42-126-110(121)122;3-2(4,5)1(6)7/h8-14,24-29,51-52,56-60,68-84,88,128-129,149-152H,15-23,30-50,53-55,112-115H2,1-7H3,(H2,116,153)(H2,117,154)(H2,118,157)(H,130,166)(H,131,173)(H,132,158)(H,133,161)(H,134,160)(H,135,171)(H,136,169)(H,137,174)(H,138,159)(H,139,164)(H,140,165)(H,141,163)(H,142,162)(H,143,170)(H,144,167)(H,145,168)(H,146,175)(H,147,176)(H,148,172)(H,155,156)(H4,119,120,125)(H4,121,122,126)(H4,123,124,127);(H,6,7)/t58-,59-,60+,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,88-;/m0./s1
InChi Key
XWBPSJLDSSCNGG-QFYXJRACSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

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    1 mg

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    Product Description

    Proadrenomedullin (N-20) is a peptide comprised of amino acid residues 22-41 of rat preproadrenomedullin.1 The rat proadrenomedullin (N-20) sequence is similar to human proadrenomedullin (N-20) (Item No. 27102) but contains three amino acid substitutions at residues 5, 6, and 8 of the human proadrenomedullin (N-20) sequence.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sakata, J., Shimokubo, T., Kitamura, K., et al. Molecular cloning and biological activities of rat adrenomedullin, a hypotensive peptide. Biochem. Biophys. Res. Commun. 195(2), 921-927 (1993).