A mixture of isothiazolinone biocides
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Methylchloroisothiazolinone/Methylisothiazolinone Mixture

Item No. 27470

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-chloro-2-methyl-3(2H)-isothiazolone mixt. with 2-methyl-3(2H)-isothiazolone
CAS Number
55965-84-9
Synonyms
  • CMIT/MIT
  • MCI/MI
  • MCIT/MIT
Molecular Formula
C4H5NOS • C4H4ClNOS
Formula Weight
264.7
Formulation (Request formulation change)
A 14% (w/v) aqueous solution
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
CN(SC(Cl)=C1)C1=O.CN(SC=C2)C2=O
InChi Code
InChI=1S/C4H4ClNOS.C4H5NOS/c1-6-4(7)2-3(5)8-6;1-5-4(6)2-3-7-5/h2H,1H3;2-3H,1H3
InChi Key
QYYMDNHUJFIDDQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 ml

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    25 ml

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    100 ml

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    Product Description

    Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) is a mixture of isothiazolinone-derived biocides.1,2 It is effective against Gram-positive and Gram-negative bacteria with MIC values of 0.0002, 0.0002, 0.00005, and 0.00005% (w/w) for S. aureus, P. aeruginosa, A. niger, and C. albicans, respectively.2 MCIT/MIT can elicit contact sensitization.3 Formulations containing MCIT/MIT have been used for controlling microbial growth in industrial and household products.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Frenzel, E., Schmidt, S., Niederweis, M., et al. Importance of porins for biocide efficacy against Mycobacterium smegmatis. Appl. Environ. Microbiol. 77(9), 3068-3073 (2011).

    2. Lundov, M.D., Johansen, J.D., Zachariae, C., et al. Low-level efficacy of cosmetic preservatives. Int. J. Cosmet. Sci. 33(2), 190-196 (2011).

    3. Scherrer, M.A.R., and Rocha, V.B. Increasing trend of sensitization to methylchloroisothiazolinone/methylisothiazolinone (MCI/MI). An. Bras. Dermatol. 89(3), 527-528 (2014).