A sulfonamide antibiotic
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Sulfameter

Item No. 27630

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-amino-N-(5-methoxy-2-pyrimidinyl)-benzenesulfonamide
CAS Number
651-06-9
Synonyms
  • Bayrena
  • NSC 683528
  • Sulfamethoxydiazine
Molecular Formula
C11H12N4O3S
Formula Weight
280.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMF:PBS (pH 7.2) (1:5): 0.16 mg/mlDMSO: 20 mg/ml
λmax
214, 230, 272 nm
SMILES
NC1=CC=C(S(NC2=NC=C(OC)C=N2)(=O)=O)C=C1
InChi Code
InChI=1S/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)
InChi Key
GPTONYMQFTZPKC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

    $90

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    25 g

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    Cayman Chemical
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    Product Description

    Sulfameter is a long-acting sulfonamide antibiotic.1 In vitro, it is active against the bacteria D. pneumoniae, K. pneumoniae, E. coli, N. meningitidis, P. vulgaris, S. aureus, S. haemolyticus, and S. typhimurium in a disc assay.2 Sulfameter is efficacious against lethal K. pneumoniae, E. coli, P. vulgaris, D. pneumoniae, P. aeruginosa, and S. typhimurium infection in a mouse model of septicemia with 50% curative dose (CD50) values of 1.6, 5.2, 5.4, 120.5, 19.1, and 88 mg/kg, respectively. Formulations containing sulfameter have previously been used in the treatment of urinary tract infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gibson, G.R. Clinical evaluation of sulphamethoxydiazine. Med. J. Aust. 2, 172-174 (1964).

    2. Böhni, E., Fust, B., Rieder, J., et al. Comparative toxicological, chemotherapeutic and pharmacokinetic studies with sulphormethoxine and other sulphonamides in animals and man. Chemotherapy 14(4), 195-226 (1969).