A sulfonamide antibiotic and PABA antimetabolite
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Sulfalene

Item No. 46329

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-amino-N-(3-methoxy-2-pyrazinyl)-benzenesulfonamide
CAS Number
152-47-6
Synonyms
  • NSC 110433
  • Sulfamethoxypyrazine
Molecular Formula
C11H12N4O3S
Formula Weight
280.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Soluble: ≥10 mg/ml
SMILES
NC1=CC=C(S(NC2=NC=CN=C2OC)(=O)=O)C=C1
InChi Code
InChI=1S/C11H12N4O3S/c1-18-11-10(13-6-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)
InChi Key
KXRZBTAEDBELFD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $29

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    100 mg

    $46

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    250 mg

    $94

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    500 mg

    $131

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    Cayman Chemical
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    Product Description

    Sulfalene is a sulfonamide antibiotic and an antimetabolite of p-aminobenzoic acid (PABA; Item No. 18659).1,2 It is active against dapsone-sensitive Mycobacterium sp. 607 (MIC = 3.6 nmol/ml), also known as M. smegmatis, and P. knowlesi in vitro. Sulfalene (0.5 mg/kg) cures parasitemia in P. knowlesi-infected rhesus monkeys.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Colwell, W.T., Chan, G., Brown, V.H., et al. Potential antileprotic agents. 1. Inhibition of a model mycobacterial system by diaryl sulfones. J. Med. Chem. 17(1), 142-144 (1974).

    2. McCormick, G.J., Canfield, C.J., and Willet, G.P. Plasmodium knowlesi: In vitro evaluation of antimalarial activity of folic acid inhibitors. Exp. Parasitol. 30(1), 88-93 (1971).

    3. Rothe, W.E., Jacobus, D.P., and Walter, W.G. Treatment of trophozoite-induced Plasmodium knowlesi infection in the rhesus monkey with Trimethoprim and sulfalene. Am. J. Trop. Med. Hyg. 18(4), 491-494 (1969).