An inactive derivative of WM-1119
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MOZ-IN-2

Item No. 27686

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(phenylsulfonyl)hydrazide 2-fluoro-5-(4-pyridazinyl)-benzoic acid
CAS Number
2055397-88-9
Synonyms
  • WM-2474
Molecular Formula
C17H13FN4O3S
Formula Weight
372.4
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
λmax
260 nm
SMILES
FC1=C(C(NNS(C2=CC=CC=C2)(=O)=O)=O)C=C(C=C1)C3=CN=NC=C3
InChi Code
InChI=1S/C17H13FN4O3S/c18-16-7-6-12(13-8-9-19-20-11-13)10-15(16)17(23)21-22-26(24,25)14-4-2-1-3-5-14/h1-11,22H,(H,21,23)
InChi Key
WYMCVPPNOFFNGE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $32

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    5 mg

    $94

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    10 mg

    $172

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    25 mg

    $388

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    Product Description

    MOZ-IN-2 is an inactive derivative of WM-1119, an inhibitor of lysine acetyltransferase 6A (KAT6A), also known as monocytic leukemia zinc finger protein (MOZ).1 It does not inhibit KAT6A (IC50 = >125 µM). See the Structural Genomics Consortium (SGC) website for more information.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Priebbenow, D.L., Leaver, D.J., Nguyen, N., et al. Discovery of acylsulfonohydrazide-derived inhibitors of the lysine acetyltransferase, KAT6A, as potent senescence-inducing anti-cancer agents. J. Med. Chem. 63(9), 4655-4684 (2020).