A major metabolite of valsartan
Related Products
Parent Compound(s)
14178Valsartan
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4-hydroxy Valsartan

Item No. 27849

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(4-hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
CAS Number
188259-69-0
Synonyms
  • CGP 71580
  • Valeryl 4-hydroxy Valsartan
Molecular Formula
C24H29N5O4
Formula Weight
451.5
Purity
≥98% (mixture of diastereomers)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: slightly soluble
SMILES
O=C(CCC(O)C)N([C@@](C(O)=O)([H])C(C)C)CC1=CC=C(C2=CC=CC=C2C3=NNN=N3)C=C1
InChi Code
InChI=1S/C24H29N5O4/c1-15(2)22(24(32)33)29(21(31)13-8-16(3)30)14-17-9-11-18(12-10-17)19-6-4-5-7-20(19)23-25-27-28-26-23/h4-7,9-12,15-16,22,30H,8,13-14H2,1-3H3,(H,32,33)(H,25,26,27,28)/t16?,22-/m0/s1
InChi Key
ICSQZMPILLPFKC-XLDIYJRPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    2.5 mg

    $436

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    Product Description

    4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan (Item No. 14178).1 It reduces platelet aggregation induced by epinephrine (Item No. 21245) and collagen but not ADP in human whole blood.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Serebruany, V.L., Malinin, A.I., Lowry, D.R., et al. Effects of valsartan and valeryl 4-hydroxy valsartan on human platelets: a possible additional mechanism for clinical benefits. J. Cardiovasc. Parmacol. 43(5), 677-684 (2004).