A diacylglycerol
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1,2-Dimyristoyl-rac-glycerol

Item No. 28171

Technical Information
Formal Name
tetradecanoic acid, 1,1'-[1-(hydroxymethyl)-1,2-ethanediyl] ester
CAS Number
20255-94-1
Synonyms
  • 1,2-Dimyristin
  • TG(14:0/14:0/0:0)
Molecular Formula
C31H60O5
Formula Weight
Purity
≥98%
A solid
Chloroform: Soluble
SMILES
OCC(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O
InChi Code
InChI=1S/C31H60O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-30(33)35-28-29(27-32)36-31(34)26-24-22-20-18-16-14-12-10-8-6-4-2/h29,32H,3-28H2,1-2H3
InChi Key
JFBCSFJKETUREV-UHFFFAOYSA-N
Side Chain Carbon Sum
28:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    1,2-Dimyristoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 and sn-2 positions. It increases phosphorylation of the insulin receptor in IM-9 cells when used at a concentration of 100 μg/ml.1 In vivo, 1,2-dimyristoyl-rac-glycerol (0.5 mg/kg) reduces tumor weight in an LY5178Y mouse xenograft model.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Grunberger, G., and Levy, J. Diacylglycerols modulate phosphorylation of the insulin receptor from human mononuclear cells. Eur. J. Biochem. 187(1), 191-198 (1990).

    2. Fukusen, N., Kido, H., Kato, Y., et alDiacylglycerols enhance the anti-tumor effect of glucocorticoid on L5178Y lymphoblasts in vivo. Jpn. J. Cancer Res. 80(10), 963-967 (1989).