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ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICESAmitraz is a formamidine acaricide.1 It induces mortality and reduces fecundity in adult R. annulatus when used at a concentration of 300 ppm. It is lethal to adult H. bipinosa (LC50 = 181 ppm). Amitraz (100 µM) reduces viability of primary rat hippocampal cells.2 In vivo, amitraz (170 mg/kg) increases malondialdehyde (MDA) and nitric oxide (NO) levels and decreases superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX) activities in rat liver, kidney, brain, spleen, and testis.3 Dietary administration of amitraz reduces larval weight and larval and pupal survival in honey bee (A. mellifera) populations.4 Formulations containing amitraz have been used as insecticides in residential, agricultural, and veterinary settings.
WARNING This product is not for human or veterinary use.
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