A fungal metabolite
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Phomalactone

Item No. 28854

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5S,6S)-5,6-dihydro-5-hydroxy-6-(1E)-1-propen-1-yl-2H-pyran-2-one
CAS Number
28921-94-0
Synonyms
  • (+)-Phomalactone
Molecular Formula
C8H10O3
Formula Weight
154.2
Purity
≥70%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Dichloromethane: solubleDMSO: solubleEthanol: soluble
SMILES
O=C1C=C[C@H](O)[C@H](/C=C/C)O1
InChi Code
InChI=1S/C8H10O3/c1-2-3-7-6(9)4-5-8(10)11-7/h2-7,9H,1H3/b3-2+/t6-,7-/m0/s1
InChi Key
OKDRUMBNXIYUEO-VHJVCUAWSA-N
Origin
Fungus/Nigrospora sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $404

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    Product Description

    Phomalactone is a fungal metabolite that has been found in N. sphaerica and has fungicidal activity.1,2 It is active against strains of the plant pathogenic fungi C. sasaki, P. graminicola, M. griesea, P. capsica, and P. infestans (IC50s = 200, 120, 83, 120, and 0.83 mg/L, respectively), but not F. oxysporum, A. alternate, B. cinerea, or C. gloeosporioides (IC50s = >200 mg/L for all).1 Phomalactone is also active against the plant pathogenic fungi A. niger and O. minus (MICs = 62.5 and 125 µg/ml, respectively).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kim, J.-C., Choi, G.J., Park, J.-H., et al. Activity against plant pathogenic fungi of phomalactone isolated from Nigrospora sphaerica. Pest Manag. Sci. 57(6), 554-559 (2001).

    2. Wu, S.-H., Chen, Y.-W., Shao, S.-C., et al. Two new solanapyrone analogues from the endophytic fungus Nigrospora sp. YB-141 of Azadirachta indica. Chem. Biodivers. 6(1), 79-85 (2009).