A dopamine receptor agonist
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N,N-Dipropyldopamine (hydrobromide)

Item No. 28937

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[2-(dipropylamino)ethyl]-1,2-benzenediol, monohydrobromide
CAS Number
65273-66-7
Molecular Formula
C14H23NO2 • HBr
Formula Weight
318.2
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
λmax
283 nm
SMILES
OC1=C(O)C=CC(CCN(CCC)CCC)=C1
InChi Code
InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3
InChi Key
LMYSNFBROWBKMB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $54

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    5 mg

    $238

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    10 mg

    $418

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    25 mg

    $783

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    Product Description

    N,N-Dipropyldopamine is a dopamine receptor agonist.1,2,3 It decreases dihydrophenylalanine (DOPA) levels in the limbic forebrain and striatum of reserpinized rats (ED50s = 25 and 20 µmol/kg, respectively), as well as reduces homovanillic acid (HVA; Item No. 27307) levels in rat striatum when administered at a dose of 80 µmol/kg.1 N,N-Dipropyldopamine (0.5-16 mg/kg) reduces spontaneous locomotor activity in mice, an effect that can be reversed by the antipsychotic spiroperidol.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wikström, H., Lindberg, P., Martinson, P., et al. Pivaloyl esters of N,N-dialkylated dopamine congeners. Central dopamine-receptor stimulating activity. J. Med. Chem. 21(9), 864-867 (1978).

    2. Feenstra, M.G., Rollema, H., Horn, A.S., et al. Effect of dihydroxy-2-aminotetralin derivatives on dopamine metabolism in the rat striatum. Naunyn Schmiedebergs Arch. Pharmacol. 310(3), 219-225 (1980).

    3. Costall, B., Lim, S.K., and Naylor, R.J. Characterisation of the mechanisms by which purported dopamine agonists reduce spontaneous locomotor activity of mice. Eur. J. Pharmacol. 73(2-3), 175-188 (1981).