A natural non-caloric sweetener
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Isomer(s)
36513Steviolbioside
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Rubusoside

Item No. 29040

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(4α)-13-(β-D-glucopyranosyloxy)-kaur-16-en-18-oic acid, β-D-glucopyranosyl ester
CAS Number
64849-39-4
Molecular Formula
C32H50O13
Formula Weight
642.7
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 10 mg/mg
SMILES
C[C@]([C@]1([H])CC2)(CCC[C@@]1(C)C(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)=O)[C@@]4([H])[C@]2(CC5=C)C[C@@]5(O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)CC4
InChi Code
InChI=1S/C32H50O13/c1-15-11-31-9-5-18-29(2,7-4-8-30(18,3)28(41)44-26-24(39)22(37)20(35)16(12-33)42-26)19(31)6-10-32(15,14-31)45-27-25(40)23(38)21(36)17(13-34)43-27/h16-27,33-40H,1,4-14H2,2-3H3/t16-,17-,18+,19+,20-,21-,22+,23+,24-,25-,26+,27+,29-,30-,31-,32+/m1/s1
InChi Key
YWPVROCHNBYFTP-OSHKXICASA-N
Origin
Plant/Malus hupehensis Rehd.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    Rubusoside is a natural non-caloric sweetener and glycoside form of steviol (Item No. 10011344) that has been found in S. rebaudiana leaves and has diverse biological activities.1,2 It inhibits glucose transport by glucose transporter 1 (Glut1) and fructose transport by Glut5 (IC50s = 4.6 and 6.7 mM, respectively, for the recombinant human transporters).3 Rubusoside prevents lipotoxicity induced by palmitic acid (Item No. 10006627) in INS-1 mouse insulinoma cells when used at concentrations ranging from 50 to 200 µM.4 It has been used to enhance the solubility of the anticancer agent etoposide (Item No. 12092).5

    WARNING This product is not for human or veterinary use.