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ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICESMethoxyfenozide is a diacylhydrazine insecticide.1 It selectively binds to lepidopteran ecdysone receptors (EcRs) over dipteran EcRs with Kd values of 0.5 and 124 nM, respectively. Dietary administration of methoxyfenozide is lethal to neonatal larvae of S. exigua, S. frugiperda, T. ni, O. nubilalis, L. pomonella, H. zea, and H. virescens (LC50s = 0.35, 0.2, 0.11, 0.18, 0.21, 0.79, and 3.12 mg/L, respectively). It induces early molting in O. nubilalis neonatal larvae when used at concentrations ranging from 0.063 to 0.5 ppm.2 Formulations containing methoxyfenozide have been used as insecticides in agriculture.
WARNING This product is not for human or veterinary use.
1. The chemical and biological properties of methoxyfenozide, a new insecticidal ecdysteroid agonist. Pest Manag. Sci. 57(2), 115-119 (2001).
2. Effect of the nonsteroidal ecdysone agonists, methoxyfenozide and tebufenozide, on the European corn borer (Lepidoptera: Pyralidae). J. Econ. Entomol. 90(6), 1486-1492 (1997).