A diacylhydrazine insecticide
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Methoxyfenozide

Item No. 29182

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-methoxy-2-methyl-benzoic acid, 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide
CAS Number
161050-58-4
Synonyms
  • RG-102398
  • RH-2485
Molecular Formula
C22H28N2O3
Formula Weight
368.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMF:PBS (pH 7.2) (1:6): 0.1 mg/mlDMSO: 20 mg/mlEthanol: 10 mg/ml
SMILES
COC1=CC=CC(C(NN(C(C)(C)C)C(C2=CC(C)=CC(C)=C2)=O)=O)=C1C
InChi Code
InChI=1S/C22H28N2O3/c1-14-11-15(2)13-17(12-14)21(26)24(22(4,5)6)23-20(25)18-9-8-10-19(27-7)16(18)3/h8-13H,1-7H3,(H,23,25)
InChi Key
QCAWEPFNJXQPAN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Methoxyfenozide is a diacylhydrazine insecticide.1 It selectively binds to lepidopteran ecdysone receptors (EcRs) over dipteran EcRs with Kd values of 0.5 and 124 nM, respectively. Dietary administration of methoxyfenozide is lethal to neonatal larvae of S. exigua, S. frugiperda, T. ni, O. nubilalis, L. pomonella, H. zea, and H. virescens (LC50s = 0.35, 0.2, 0.11, 0.18, 0.21, 0.79, and 3.12 mg/L, respectively). It induces early molting in O. nubilalis neonatal larvae when used at concentrations ranging from 0.063 to 0.5 ppm.2 Formulations containing methoxyfenozide have been used as insecticides in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Carlson, G.R., Dhadialla, T.S., Hunter, R., et al. The chemical and biological properties of methoxyfenozide, a new insecticidal ecdysteroid agonist. Pest Manag. Sci. 57(2), 115-119 (2001).

    2. Trisyono, A., and Chippendale, M.G. Effect of the nonsteroidal ecdysone agonists, methoxyfenozide and tebufenozide, on the European corn borer (Lepidoptera: Pyralidae). J. Econ. Entomol. 90(6), 1486-1492 (1997).