An MT2 receptor antagonist
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Product Type

Small Molecule Modulators
Receptor Pharmacology
Antagonists

Research Area

DH 97

Item No. 29522

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[3-(2-aminoethyl)-2-(phenylmethyl)-1H-indol-1-yl]-1-pentanone
CAS Number
343263-95-6
Molecular Formula
C22H26N2O
Formula Weight
334.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
λmax
225, 283 nm
SMILES
O=C(CCCC)N1C(CC2=CC=CC=C2)=C(CCN)C3=CC=CC=C31
InChi Code
InChI=1S/C22H26N2O/c1-2-3-13-22(25)24-20-12-8-7-11-18(20)19(14-15-23)21(24)16-17-9-5-4-6-10-17/h4-12H,2-3,13-16,23H2,1H3
InChi Key
WQQBIBNCSCLVDX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $41

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    5 mg

    $108

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    10 mg

    $157

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    25 mg

    $341

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    Product Description

    DH 97 is an antagonist of melatonin receptor 2 (MT2; Kis = 252 and 1,100 for human MT2 and MT1 receptors, respectively).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nosjean, O., Nicolas, J.P., Klupsch, F., et al. Comparative pharmacological studies of melatonin receptors: MT1, MT2 and MT3/QR2. Tissue distribution of MT3/QR2. Biochem. Pharmacol. 61(11), 1369-1379 (2001).