A fungal metabolite with diverse biological activities
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Monocerin

Item No. 29572

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2S,3aR,9bR)-2,3,3a,9b-tetrahydro-6-hydroxy-7,8-dimethoxy-2-propyl-5H-furo[3,2-c][2]benzopyran-5-one
CAS Number
30270-60-1
Synonyms
  • (+)-Monocerin
Molecular Formula
C16H20O6
Formula Weight
308.3
Purity
≥70%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Dichloromethane: solubleDMSO: solubleEthanol: solubleMethanol: soluble
SMILES
COC1=C(OC)C(O)=C(C(O[C@@]2([H])[C@]3([H])O[C@@H](CCC)C2)=O)C3=C1
InChi Code
InChI=1S/C16H20O6/c1-4-5-8-6-11-14(21-8)9-7-10(19-2)15(20-3)13(17)12(9)16(18)22-11/h7-8,11,14,17H,4-6H2,1-3H3/t8-,11+,14+/m0/s1
InChi Key
VAYQNUBOZLPGDH-OLXJLDBKSA-N
Origin
Fungus/Unidentified sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Monocerin is a fungal metabolite that has been found in F. larvarum and has diverse biological activities.1,2,3 It is active against the bacteria E. coli and B. megaterium, the phytopathogenic fungus M. violaceum, and the alga C. fusca in an agar diffusion assay when used at a concentration of 50 µg/disc.1 Monocerin (17.5 µg/ml) induces mortality in adult C. erythrocephala.2 It reduces root elongation in pre-germinated S. halepense seeds when used at a concentration of 33 ppm.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhang, W., Krohn, K., Draeger, S., et al. Bioactive isocoumarins isolated from the endophytic fungus Microdochium bolleyi. J. Nat. Prod. 71(6), 1078-1081 (2008).

    2. Claydon, N., Grove, J.F., and Pople, M. Insecticidal secondary metabolic products from the entomogenous fungus Fusarium larvarum. J. Invertebr. Pathol. 33(3), 364-367 (1979).

    3. Robeson, D.J., and Strobel, G.A. Monocerin, a phytotoxin from Exserohilum turcicum (Drechslera turcica). Agr. BioI. Chem. 46(11), 2681-2683 (1982).