A fungal metabolite with fungicidal and herbicidal activities
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Carbolactone

Item No. 29838

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5α)-3β,12β-dihydroxy-4,4-dimethyl-pregn-8-ene-20S-carboxylic acid, δ-lactone
CAS Number
155443-55-3
Molecular Formula
C24H36O3
Formula Weight
372.5
Purity
≥70%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Dichloromethane: solubleDMSO: solubleEthanol: solubleMethanol: soluble
SMILES
O=C1O[C@]([C@@]2(C)[C@@]3([H])CC[C@]2([H])[C@@H]1C)([H])CC4=C3CC[C@]5([H])[C@]4(C)CC[C@H](O)C5(C)C
InChi Code
InChI=1S/C24H36O3/c1-13-15-7-8-16-14-6-9-18-22(2,3)19(25)10-11-23(18,4)17(14)12-20(24(15,16)5)27-21(13)26/h13,15-16,18-20,25H,6-12H2,1-5H3/t13-,15+,16-,18-,19-,20+,23+,24+/m0/s1
InChi Key
ICBKTZVCTSCWTL-WYCYEJLCSA-N
Origin
Fungus/Preussia sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $549

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    Product Description

    Carbolactone is a fungal metabolite originally isolated from Sporormiella australis that has fungicidal and herbicidal activities.1 It is active against the phytopathogenic fungi U. violacea and E. repens, but not the bacteria B. megaterium or E. coli, when used at concentrations of 6.5, 65, and 650 µg/ml in an agar diffusion assay. Carbolactone also inhibits germination of the cress L. sativum.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Krohn, K., Ludewig, K., Jones, P.G., et al. Biologically active metabolites from fungi, 21 an antifungal and herbicidal lanostane lactone from Sporormiella australis. Nat. Prod. Lett. 1(1), 29-32 (2006).